Cadmium(II) Schiff base Complex Containing 5-Fluoroisatin Moiety: Synthesis, Characterization, Antibacterial Activity and Structural Studies

The Schiff base ligand, HSB5FISA (H1), obtained by the condensation of S-benzyldithiocarbazate with 5-fluoroisatin, has been employed to synthesize a new cadmium(II) complex, Cd(SB5FISA)2 (2) (SB5FISA = monoanionic form H1). complex characterized elemental analysis, molar conductivity, magnetic susceptibility, inductively coupled plasma atomic emission spectroscopy (ICP-AES), Fourier-transform infrared (FT-IR) and ultraviolet-visible (UV-Vis). crystallographic study Cd(SB5FISA)2×2DMSO (2a) (DMSO dimethyl sulfoxide) was conducted using single-crystal X-ray diffraction. crystal structure 2a confirmed presence 6-coordinated cadmium in distorted octahedral environment. Ligand H1 behaves tridentate fashion, coordinating metal centre through thiolate sulfur, azomethine nitrogen carbonyl oxygen. antibacterial activity both 2 examined against 4 different bacterial strains disc diffusion method. Complex showed significant inhibitory effect Bacillus subtilis an inhibition zone 14 mm, comparable standard antibiotic streptomycin.
 HIGHLIGHTS 
 Cd(II) 5-fluoroisatin synthesized
 Structural studies compound determined via single diffraction
 Compound exhibited towards subtilis
 GRAPHICAL ABSTRACT